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Can troponin T levels be useful in the diagnosis of rheumatic carditis?


1 Department of Pediatric Cardiology, Akdeniz University School of Medicine, Arapsuyu, Antalya, Turkey
2 Department of Pediatrics, Akdeniz University School of Medicine, Arapsuyu, Antalya, Turkey
3 Department of Biochemistry, Akdeniz University School of Medicine, Arapsuyu, Antalya, Turkey

Correspondence Address:
Firat Kardelen
Department of Pediatric Cardiologys, Akdeniz University School of Medicine, 07070, Arapsuyu, Antalya
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2069.84657

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Year : 2011  |  Volume : 4  |  Issue : 2  |  Page : 156-158

 

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Objective: Acute rheumatic fever (ARF) is an endemic disease observed in children of developing countries. The purpose of this study was to test if it was possible to identify myocardial involvement in cases with rheumatic carditis by the measurement of serum cardiac TnT. Methods: 30 patients diagnosed as ARF underwent echocardiography and their cardiac troponin T (cTnT) serum levels were measured. Patients were divided into group 1: Arthritis alone, group 2: carditis, and group 3 carditis with congestive heart failure (CHF). Results: cTnT serum levels were normal in all except one patient with in group 3. Two patients in carditis (group 2) and three patients in CHF (group 3) had dilation in left ventricular end diastolic diameter. Conclusions: Normal cTnT levels in our patient group suggests that inflammation rather than myocardial necrosis is predominant in ARF carditis.






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1 Department of Pediatric Cardiology, Akdeniz University School of Medicine, Arapsuyu, Antalya, Turkey
2 Department of Pediatrics, Akdeniz University School of Medicine, Arapsuyu, Antalya, Turkey
3 Department of Biochemistry, Akdeniz University School of Medicine, Arapsuyu, Antalya, Turkey

Correspondence Address:
Firat Kardelen
Department of Pediatric Cardiologys, Akdeniz University School of Medicine, 07070, Arapsuyu, Antalya
Turkey
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2069.84657

Rights and Permissions

Objective: Acute rheumatic fever (ARF) is an endemic disease observed in children of developing countries. The purpose of this study was to test if it was possible to identify myocardial involvement in cases with rheumatic carditis by the measurement of serum cardiac TnT. Methods: 30 patients diagnosed as ARF underwent echocardiography and their cardiac troponin T (cTnT) serum levels were measured. Patients were divided into group 1: Arthritis alone, group 2: carditis, and group 3 carditis with congestive heart failure (CHF). Results: cTnT serum levels were normal in all except one patient with in group 3. Two patients in carditis (group 2) and three patients in CHF (group 3) had dilation in left ventricular end diastolic diameter. Conclusions: Normal cTnT levels in our patient group suggests that inflammation rather than myocardial necrosis is predominant in ARF carditis.






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