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Pathology of Takayasu arteritis: A brief review


1 Department of Pathology, (Cardiovascular and Thoracic Division), Seth GS Medical College, Mumbai, Maharashtra, India
2 Department of Pathology, BJ Wadia Children's Hospital, Parel, Mumbai, Maharashtra, India

Correspondence Address:
Pradeep Vaideeswar
Department of Pathology (Cardiovascular and Thoracic Division), Seth GS Medical College, Parel, Mumbai - 400 012, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2069.107235

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Year : 2013  |  Volume : 6  |  Issue : 1  |  Page : 52-58

 

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Takayasu arteritis (TA) is a chronic idiopathic and granulomatous vasculitis, manifesting mainly as a panaortitis. Autoimmune cell-mediated immunity is probably responsible for the disease. The inflammation commences from the adventitia and progresses to the intima and leads to, both in adults and children, segmental stenosis, occlusion, dilatation, and/or aneurysm formation. This review focuses briefly on the etiopathogenesis, and describes the pathological and clinical features in adults and children.






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1 Department of Pathology, (Cardiovascular and Thoracic Division), Seth GS Medical College, Mumbai, Maharashtra, India
2 Department of Pathology, BJ Wadia Children's Hospital, Parel, Mumbai, Maharashtra, India

Correspondence Address:
Pradeep Vaideeswar
Department of Pathology (Cardiovascular and Thoracic Division), Seth GS Medical College, Parel, Mumbai - 400 012, Maharashtra
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2069.107235

Rights and Permissions

Takayasu arteritis (TA) is a chronic idiopathic and granulomatous vasculitis, manifesting mainly as a panaortitis. Autoimmune cell-mediated immunity is probably responsible for the disease. The inflammation commences from the adventitia and progresses to the intima and leads to, both in adults and children, segmental stenosis, occlusion, dilatation, and/or aneurysm formation. This review focuses briefly on the etiopathogenesis, and describes the pathological and clinical features in adults and children.






[FULL TEXT] [PDF]*


        
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