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Table of Contents   
CASE REPORT  
Year : 2013  |  Volume : 6  |  Issue : 2  |  Page : 173-175
Percutaneous device closure of persistent ductus venosus presenting with hemoptysis


Department of Cardiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India

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Date of Web Publication20-Jul-2013
 

   Abstract 

An eight-year-old boy was evaluated for unexplained hemoptysis and cyanosis. A contrast echocardiogram was suggestive of pulmonary arteriovenous fistula. Further evaluation revealed persistent ductus venosus (PDV) and aortopulmonary collaterals. Both the PDV and aortopulmonary collaterals were closed percutaneously. PDV is amenable for device closure after detailed anatomical evaluation. Prior to closure, it is important to ensure adequate portal vein arborization into the liver and normal portal pressure after test balloon occlusion.

Keywords: Pulmonary arteriovenous fistula, persistent ductus venosus, portal vein and device

How to cite this article:
Subramanian V, Kavassery MK, Sivasubramonian S, Sasidharan B. Percutaneous device closure of persistent ductus venosus presenting with hemoptysis. Ann Pediatr Card 2013;6:173-5

How to cite this URL:
Subramanian V, Kavassery MK, Sivasubramonian S, Sasidharan B. Percutaneous device closure of persistent ductus venosus presenting with hemoptysis. Ann Pediatr Card [serial online] 2013 [cited 2019 Sep 19];6:173-5. Available from: http://www.annalspc.com/text.asp?2013/6/2/173/115274



   Introduction Top


An aortopulmonary collateral is a common cause for hemoptysis in children. Pulmonary arterio venous fistula (PAVF) resulting from a portosystemic shunt can cause significant systemic hypoxemia. Here we report a rare association of PAVF and an aortopulmonary collateral in a patient with persistent ductus venosus (PDV). Both were addressed percutaneously.


   Case Report Top


An eight-year-old boy, presented with a history of hemoptysis (50 ml per episode, thrice) for one week. The X-ray of the chest was unremarkable and the screening echocardiography was normal. Pulse oximetry and blood gas showed oxygen saturation of 80%, when the patient was comfortable at rest. Contrast echo with agitated saline done to rule right to left shunt, showed delayed appearance of bubbles in the left atrium after four cycles, suggestive of pulmonary arteriovenous fistula (PAVF). Contrast-enhanced computed tomography (CECT) revealed two small (2 mm) aortopulmonary collaterals at T6 - T7, one on each side, no major PAVF, features of aspiration in the right upper lobe, and an incidentally detected persistent ductus venosus (PDV) [Figure 1]. The ultrasonogram and echocardiography confirmed a PDV of 6.5 mm diameter, opening into the inferior vena cava (IVC) [Figure 1] and [Video 1] and no evidence of liver disease or portal hypertension. The diagnosis of congenital portosystemic shunt due to PDV, causing PAVF was made. The aortopulmonary collateral arteries (APCA) were considered to be secondary to systemic hypoxemia. However, the cause of hemoptysis was not clear (aortopulmonary collateral or PAVF). The patient was taken up for percutaneous intervention of PDV and aortopulmonary collateral. A pulmonary angiogram showed diffuse bilateral multiple small PAVFs [Figure 2]. The PDV was entered from the internal jugular vein access. Test balloon occlusion showed adequate hepatic portal circulation and no increase in portal pressure from the basal 10 mmHg [Figure 3] and [Video 2]. Through a 7F Mullin sheath, a 12 mm Amplatzer vascular plug II (St. Jude Medical, St. Paul, Minnesota) was deployed [Figure 4] and [Video 3]. The APCAs on both sides were selectively cannulated [Figure 5]. The right APCA was cannulated with a 4F right coronary artery (RCA) catheter and coiled with two 035 inch 2 mm - 30 mm platinum fiber coils (COOK MEDICAL INC. Bloomington). The left APCA could not be coiled. There was no recurrence of hemoptysis in the next 48 hours and the patient was discharged. The follow-up plan was to monitor the oxygen saturation for regression of PAVF and an ultrasonogram to rule out portal hypertension.
Figure 1: Persistent ductus venosus connecting the left portal vein to the inferior vena cava. (a) Contrast-enhanced computed tomography (red arrow) (b) Subcostal two-dimensional echocardiography (yellow arrow)

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Figure 2: Right (a) and left (b) pulmonary artery angiogram showing multiple, diffuse small end-on vessels suggestive of pulmonary arteriovenous fistula

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Figure 3: Occlusion of persistent ductus venosus (yellow arrow) with a balloon wedge catheter introduced from the inferior vena cava. Balloon occlusion angiogram shows adequate portal vein ramification

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Figure 4: Subcostal two-dimensional echocardiography showing an Amplatzer vascular plug in persistent ductus venosus (red arrow)

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Figure 5: Selective right (a) and left (b) aortopulmonary collateral angiogram

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   Discussion Top


Congenital portosystemic shunts are extra hepatic (abernethy malformation) and intrahepatic (persistent patent ductus venosus). [1],[2] Portosystemic shunts result in by-passing of the liver by splanchnic circulation. It results in complications like hepatic encephalopathy, pulmonary hypertension, and hepatopulmonary syndrome (PAVF with arterial hypoxemia). The microscopic nature of PAVF, not detectable by CECT chest has been reported. [3] APCAs are usually seen in cyanotic congenital heart disease with decreased pulmonary blood flow, like Tetralogy of Fallot, with or without pulmonary atresia. Developmentally, they arise between three to four weeks of gestation and are considered to be a persistence of the fifth arch or the intersegmental arteries of the dorsal aorta. However, in the index case it is probably postnatal development due to persistent hypoxemia, due to PAVF.

Percutaneous closure of a portosystemic shunt needs detailed anatomical evaluation of the portal vein, inferior vena cava (IVC), and the connecting channel. It requires meticulous planning of the procedure with respect to vascular access, appropriate imaging, and suitable hardware. Prior to closure, it is important to ensure adequate portal vein hepatic ramification and normal portal pressure by test balloon occlusion and an angiogram. Closure of the ductus venous should be done as close to the IVC as possible, to avoid portal vein occlusion.

In conclusion, persistent ductus venosus can lead to pulmonary arteriovenous fistula and hemoptysis. Percutaneous device closure requires meticulous planning and detailed anatomical and physiological evaluation.

Video 1:



Video 2:



Video 3:



 
   References Top

1.Stringer MD. The clinical anatomy of congenital portosystemic venous shunts. Clin Anat 2008;21:147-57.  Back to cited text no. 1
    
2.Yoshimoto Y, Shimizu R, Saeki T, Harada T, Sugio Y, Nomura S, et al. Patent ductus venosus in children: A case report and review of the literature. J Pediatr Surg 2004;39:E1-5.  Back to cited text no. 2
    
3.Senguttuvan NB, Kumar J, Kothari SS. "Treatable" diffuse pulmonary arteriovenous fistula- An unusual cause. Ann Pediatr Card 2011;4:215-6.  Back to cited text no. 3
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Correspondence Address:
Venkateshwaran Subramanian
Department of Cardiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-2069.115274

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    Figures

  [Figure 1], [Figure 2], [Figure 3], [Figure 4], [Figure 5]



 

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