Anita Saxena1, Anurag Mehta2, Mamta Sharma3, Sudha Salhan4, Mani Kalaivani5, Sivasubramanian Ramakrishnan6, Rajnish Juneja6
1 All Institute of Medical Sciences, New Delhi, India
2 Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
3 Department of Pediatrics, Columbia Asia Hospital, Gurgaon, Haryana, India
4 Department of Obstetrics and Gynecology, Hindu Rao Hospital, New Delhi, India
5 Department of Biostatistics, All Institute of Medical Sciences, New Delhi, India
6 Department of Cardiology, All Institute of Medical Sciences, New Delhi, India
Objective: To assess the birth prevalence and pattern of congenital heart disease (CHD) using echocardiography in babies born in a community hospital of North India.
Methods: A cross-sectional observational study conducted over a period of 3 years. Newborns born over a specific 8-h period of the day were recruited in the study. They underwent routine clinical examination and pulse oximetry, followed by screening echocardiography for diagnosing a CHD.
Results: A total of 20,307 newborns were screened, among which 874 had abnormal echocardiograms; 687 had insignificant CHDs, 164 had significant CHDs, and 24 had other abnormal cardiac findings. The birth prevalence of significant CHDs was 8.07 per 1000 live births; 131 newborns had an acyanotic CHD (79.9%) and 33 a cyanotic CHD (20.1%). Ventricular septal defect (VSD) was the most common acyanotic CHD, present in 116 newborns, giving a prevalence of 5.7/1000 live births. Among the cyanotic CHD, transposition of great arteries was most common (prevalence 0.34/1000 live births).
Conclusion: The CHD birth prevalence in our study is similar to the reported worldwide birth prevalence. Acyanotic CHD (mostly VSD) is seen in about three-fourths of babies born with CHD. The more sinister cyanotic CHD is present in remaining 25%.
DM, Room # 29, Department of Cardiology, All India Institute of Medical Sciences, New Delhi
Source of Support: None, Conflict of Interest: None
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