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Patterns of myocardial involvement in children during COVID-19 pandemic: Early experience from northern Italy


1 Department of Cardiology, ASST Papa Giovanni XXIII, Bergamo, Italy
2 Department of Cardiology, ASST Papa Giovanni XXIII, Bergamo, Italy; University of studies of Milan, Italy

Correspondence Address:
Dr. Paolo Ferrero
Department of Cardiology, ASST Papa Giovanni XXIII, Piazza OMS, 1, 24127 Bergamo
Italy
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/apc.APC_77_20

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Year : 2020  |  Volume : 13  |  Issue : 3  |  Page : 230-233

 

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There is limited information about coronavirus disease 2019 (COVID-19) in the pediatric population. Preliminary data suggest a not insignificant prevalence of cardiac involvement. Here, we report our early experience with COVID-19 in the pediatric population. These patients display exceptionally high levels of acute-phase reactants. The clinical syndrome in these patients is somewhat similar to Kawasaki disease with or without myocardial involvement. In some cases, the presentation mimics typical myocarditis. Severe myocardial involvement is associated with transient electrocardiographic and echocardiographic abnormalities. These findings may be due to the cardiotropic nature of the virus or may be the result of an immunologic response to the infection.






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1 Department of Cardiology, ASST Papa Giovanni XXIII, Bergamo, Italy
2 Department of Cardiology, ASST Papa Giovanni XXIII, Bergamo, Italy; University of studies of Milan, Italy

Correspondence Address:
Dr. Paolo Ferrero
Department of Cardiology, ASST Papa Giovanni XXIII, Piazza OMS, 1, 24127 Bergamo
Italy
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/apc.APC_77_20

Rights and Permissions

There is limited information about coronavirus disease 2019 (COVID-19) in the pediatric population. Preliminary data suggest a not insignificant prevalence of cardiac involvement. Here, we report our early experience with COVID-19 in the pediatric population. These patients display exceptionally high levels of acute-phase reactants. The clinical syndrome in these patients is somewhat similar to Kawasaki disease with or without myocardial involvement. In some cases, the presentation mimics typical myocarditis. Severe myocardial involvement is associated with transient electrocardiographic and echocardiographic abnormalities. These findings may be due to the cardiotropic nature of the virus or may be the result of an immunologic response to the infection.






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