Year : 2018  |  Volume : 11  |  Issue : 1  |  Page : 17--27

Normal reference ranges for cardiac valve cross-sectional areas in preterm infants


Lulu Abushaban1, Mariappa Thinakar Vel2, Jebaraj Rathinasamy2, Prem N Sharma3 
1 Department of Pediatric Cardiology, Chest Diseases Hospital, Ministry of Health, Faculty of Medicine, Kuwait University, Kuwait
2 Department of Pediatric Cardiology, Chest Diseases Hospital, Ministry of Health, Kuwait
3 Department of Biostatistics, Faculty of Medicine, Kuwai University, Kuwait

Correspondence Address:
Prof. Lulu Abushaban
Consultant Pediatric Cardiologist, Chest Diseases Hospital, Professor in Pediatric Cardiology, Kuwait University
Kuwait

Objective : To establish normal reference ranges for cardiac valve crosssectional areas (CSAs) in preterm infants and their correlation with gestational age, body weight, and chronological age. Materials and Methods : In a prospective study, 268 preterm babies fulfilling the criteria for inclusion were examined. Echocardiograms were performed to measure aortic, pulmonary, mitral, and tricuspid valve CSAs on 0–6 day (s) of life and at weekly intervals until they reached 36 weeks. Gestational age was divided into three groups, 24–27, 28–31, and 32–35 weeks, and body weight was divided into five groups, ≤999, 1000–1499, 1500–1999, 2000–2499, and ≥2500 g. Overall group differences were compared for each period of life: 0–6 days and 1–2, 3–4, and ≥5 weeks. Results : The mean gestational age was 29.8 (±2.38 standard deviation [SD]) weeks, ranging between 24 and 35 weeks, and the mean body weight was 1479 (±413 SD) g, ranging between 588 and 3380 g. All cardiac valve CSAs correlated well with body weight. A significant gradual increase was observed in all valve CSAs with body weight during each period of life. Overall, a progressive and significant increase in all valve CSAs was observed during the first 9 weeks of life. Conclusions : Cardiac valve CSAs were found to be significantly correlated with body weight. The study also provides reference data, which can be used as a normal reference tool for valve CSAs in preterm infants against gestational age, body weight, and chronological age.


How to cite this article:
Abushaban L, Vel MT, Rathinasamy J, Sharma PN. Normal reference ranges for cardiac valve cross-sectional areas in preterm infants.Ann Pediatr Card 2018;11:17-27


How to cite this URL:
Abushaban L, Vel MT, Rathinasamy J, Sharma PN. Normal reference ranges for cardiac valve cross-sectional areas in preterm infants. Ann Pediatr Card [serial online] 2018 [cited 2018 Dec 18 ];11:17-27
Available from: http://www.annalspc.com/article.asp?issn=0974-2069;year=2018;volume=11;issue=1;spage=17;epage=27;aulast=Abushaban;type=0