Ziadi Jalel, Mleyhi Sobhi, Ben Omrane Skander, Khayati Adel
Department of Cardiovascular and Thoracic, Rabta Hospital, Medical University of Tunis, Tunis, Tunisia
Familial hypercholesterolemia (FH) is a dominantly inherited disorder caused by mutation at the locus for the low-density lipoprotein (LDL) receptor and is frequently associated with premature coronary artery disease and aortic valve involvement. The surgical treatment of these complications is accompanied by a high degree of risk, even in skillful hands. An intensive cholesterol-lowering therapy and LDL aphaeresis in association with surgery may be useful. The case of a 12-year-old girl, with a medical history of familial hypercholesterolemia is reported here, operated two years previously for valvular aortic stenosis; Ross intervention was done. She was readmitted for acute coronary syndrome. Three coronary artery bypass grafting was performed with saphenous veins with positive results.
Cardiovascular and Thoracic Department, Rabta Hospital, Jebbari Street, 1001 Tunis
Source of Support: None, Conflict of Interest: None
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