Year : 2008  |  Volume : 1  |  Issue : 1  |  Page : 18--26

Long QT syndrome: A therapeutic challenge

Maully Shah, Christopher Carter 
 The Cardiac Center, The Children's Hospital of Philadelphia, Philadelphia, USA

Correspondence Address:
Christopher Carter
The Cardiac Center, The Children«SQ»s Hospital of Philadelphia 34th and Civic Center Blvd Philadelphia, PA 19104

Congenital long QT syndrome (LQTS) is one of the most common cardiac channelopathies and is characterized by prolonged ventricular repolarization and life-threatening arrhythmias. The mortality is high among untreated patients. The identification of several LQTS genes has had a major impact on the management strategy for both patients and family members. An impressive genotype-phenotype correlation has been noted and genotype identification has enabled genotype specific therapies. Beta blockers continue to be the primary treatment for prevention of life threatening arrhythmias in the majority of patients. Other therapeutic options include pacemakers, implantable cardioverter defibrillators, left cardiac sympathetic denervation, sodium channel blocking medications and lifestyle modification.

How to cite this article:
Shah M, Carter C. Long QT syndrome: A therapeutic challenge.Ann Pediatr Card 2008;1:18-26

How to cite this URL:
Shah M, Carter C. Long QT syndrome: A therapeutic challenge. Ann Pediatr Card [serial online] 2008 [cited 2022 Jul 3 ];1:18-26
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