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July-December 2009 Volume 2 | Issue 2
Page Nos. 109-181
Online since Saturday, December 12, 2009
Accessed 82,989 times.
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EDITORIAL |
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Are we shy of clinical research in India? |
p. 109 |
Bharat Dalvi DOI:10.4103/0974-2069.58310 PMID:20808621 |
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ORIGINAL ARTICLE |
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Emergency balloon dilation or stenting of critical coarctation of aorta in newborns and infants: An effective interim palliation |
p. 111 |
Edwin Francis, S Gayathri, Balu Vaidyanathan, B.R.J Kannan, R Krishna Kumar DOI:10.4103/0974-2069.58311 PMID:20808622Background: Management of native uncomplicated coarctation in neonates remains controversial with current evidence favoring surgery. The logistics of organizing surgical repair at short notice in sick infants with critical coarctation can be challenging.
Methods and Results: We reviewed data of 10 infants (mean age of 2.9 ±1.6 weeks) who underwent catheter intervention for severe coarctation and left ventricular (LV) dysfunction between July 2003 and August 2007. Additional cardiac lesions were present in 7. Mean systolic gradient declined from 51±12 mm Hg to 8.7±6.7 mm Hg after dilation. The coarctation segment was stented in five patients. Procedural success was achieved in all patients with no mortality. Complications included brief cardiopulmonary arrest (n =1), sepsis (n = 1) and temporary pulse loss (n = 2). LV dysfunction improved in all patients. Average ICU stay was 5±3.4 days and hospital stay was 6.5±3.4 days. On follow-up (14.1±10.5 months), all developed restenosis after median period of 12 weeks (range four to 28 weeks). Three (two with stents) underwent elective coarctation repair, two underwent ventricular septal defect (VSD) closure and coarctation repair and one underwent pulmonary artery (PA) banding. Two patients who developed restenosis on follow-up were advised surgery, but did not report. Two (one with stent) underwent redilatation and are being followed with no significant residual gradients.
Conclusion : Balloon dilation ± stenting is an effective interim palliation for infants and newborns with critical coarctation and LV dysfunction. Restenosis is inevitable and requires to be addressed. |
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INVITED COMMENTS |
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Transcatheter interventions in critically ill neonates and infants with aortic coarctation |
p. 116 |
P Syamasundar Rao DOI:10.4103/0974-2069.58312 PMID:20808623 |
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ORIGINAL ARTICLE |
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Role of prophylactic surgical ligation of patent ductus arteriosus in extremely low birth weight infants: Systematic review and implications for clinical practice  |
p. 120 |
Rafat Mosalli, Khalid AlFaleh, Bosco Paes DOI:10.4103/0974-2069.58313 PMID:20808624Objectives :To investigate the effectiveness and safety of prophylactic surgical ligation of patent ductus arteriosus (PDA) on mortality and morbidity of preterm infants weighing less than 1000 g at birth.
Materials :The study conducted a systematic search of available database from 1996-2008. Retrieved articles were assessed for eligibility and data was abstracted independently by two reviewers. Decisions to include studies for review and the methodological quality of included studies were asssessed in duplicate based on predetermined criteria. No language restrictions were applied.
Results :Only one eligible study that enrolled 84 extremely low birth weight infants was identified. Prophylactic surgical ligation of PDA resulted in a statistically significant reduction of severe stage II or III necrotizing enterocolitis, [RR 0.25, 95% CI (0.08, 0.83), P value 0.02, number needed to treat 5]. The study, however, found no statistically significant difference in mortality, intraventricular hemorrhage, bronchopulmonary dysplasia, and retinopathy of prematurity.
Conclusions :Current evidence does not support the use of prophylactic surgical ligation of PDA in the management of the preterm infants. |
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REVIEW ARTICLE |
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Role of myocardial perfusion single photon emission computed tomography in pediatric cardiology practice |
p. 127 |
P Shanmuga Sundaram, S Padma DOI:10.4103/0974-2069.58314 PMID:20808625Diagnostic and prognostic power of myocardial perfusion imaging in patients with coronary artery disease has been demonstrated with planar imaging which was further improvised with addition of gated SPECT and newer Technetium labeled myocardial perfusion tracers like SestaMIBI, Tetrofosmin. Myocardial perfusion abnormalities at rest and after stress are considered to be the best predictors of cardiac event-free survival in adults with ischemic heart disease. This article highlights various myocardial perfusion imaging (MPI)radiopharmaceuticals, exercise procedures, pharmacological stress protocols, indications for MPI and myocardial perfusion patterns in children with some of the common congenital and acquired heart diseases. |
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PERSPECTIVE |
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Teamwork in pediatric heart care |
p. 140 |
R Krishna Kumar DOI:10.4103/0974-2069.58315 PMID:20808626Pediatric cardiac specialties, pediatric cardiology (pediatric cardiac surgery and pediatric cardiac anesthesiology and intensive care) are only now being recognized as distinct specialties in most parts of the world. There has been a tremendous growth in knowledge in these specialties in the last 30-40 years with dramatic improvements in outcome.
Pediatric cardiac care thrives on team work. The cohesiveness of the team of caregivers has a direct impact on the patient outcomes and efficiency of the system. The development of hybrid heart procedures in pediatric heart care represents an important benchmark in a team-based approach to patient care where a group of specialists with specific skills work closely together for ensuring the best possible patient outcome. Establishment of a cohesive team requires organization of group of team members with diverse skills to come together through good mutual understanding, under a leadership that actively promotes team harmony. Excellent communication among team members is a core requirement. The barriers for development and sustenance of a successful team must be recognized and overcome. They include egos of key team members as a source of conflict, time for interactions, disproportionate rewards and recognition for members of the team and traditional hierarchical arrangements. Special attention must be paid to motivating non-physician staff. |
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DOWN MEMORY LANE |
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Musings on a quarter of a century in pediatric cardiac technology |
p. 146 |
Roger Restall DOI:10.4103/0974-2069.58316 PMID:20808627 |
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OPINION POLL |
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Digoxin in management of heart failure in children: Should it be continued or relegated to the history books?  |
p. 149 |
Shreepal Jain, Balu Vaidyanathan DOI:10.4103/0974-2069.58317 PMID:20808628 |
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CASE REPORTS |
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Supracardiac anomalous pulmonary venous connection with unilateral pulmonary venous atresia: Diagnosis and management |
p. 153 |
Vishal P Changela, Suresh Pujar, Sunita Maheshwari DOI:10.4103/0974-2069.58318 PMID:20808629We report a case of a 6-day-old neonate referred to us for surgical correction of total anomalous pulmonary venous connection. Meticulous evaluation contributed to accurate diagnosis of associated unilateral pulmonary venous atresia. This unique association provides insights into the importance of evaluation of all pulmonary veins using various imaging tools. |
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Radiofrequency ablation in an infant with recurrent supraventricular tachycardia and cyanosis |
p. 156 |
Amit Vora, Yash Lokhandwala, Chirag Sheth, Bharat Dalvi DOI:10.4103/0974-2069.58319 PMID:20808630We report an unusual presentation of supraventricular tachycardia, in an infant, with cyanosis. The child had atrial septal defect with hypoplastic right ventricle. Radiofrequency ablation was performed in view of drug resistant SVT |
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Transcatheter closure of patent ductus arteriosus and interruption of inferior vena cava with azygous continuation using an Amplatzer duct occluder II |
p. 159 |
Ghee Tiong Koh, Sharifah AI Mokthar, Amir Hamzah, Jasvinder Kaur DOI:10.4103/0974-2069.58320 PMID:20808631We report a case of transcatheter closure of patent ductus arteriosus using the new Amplatzer duct occluder II in an adult patient with interrupted inferior vena cava with azygous continuation via the femoral artery approach. |
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Percutaneous closure of patent ductus arteriosus via internal jugular vein in patient with interrupted inferior vena cava |
p. 162 |
Nehal H Patel, Tarun H Madan, Amar M Panchal, Bhavesh M Thakkar DOI:10.4103/0974-2069.58321 PMID:20808632Transcatheter closure of patent ductus arteriosus (PDA) using various occluders and coils via femoral vein is a well established therapeutic option. However, in patients with interrupted inferior vena cava (IVC) it is not feasible to close the PDA percutaneously using traditional methods. We present a nine-year-old girl with IVC interruption in whom percutaneous closure of PDA was successfully accomplished via the transjugular approach. |
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Williams syndrome and Ebstein's anomaly: A rare association |
p. 165 |
Vishal Changela, Sunita Maheshwari, Meenakshi Bhat DOI:10.4103/0974-2069.58322 PMID:20808633We report a rare case of Williams syndrome associated with Ebstein's anomaly of the tricuspid valve. To our knowledge, such an association has never been reported. |
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Renal artery stenosis due to neurofibromatosis |
p. 167 |
Ishwar Chandra Malav, SS Kothari DOI:10.4103/0974-2069.58323 PMID:20808634A 4-year-old boy with hypertension due to renal artery stenosis and neurofibromatosis type 1 is presented for its rarity. Renal artery stenosis due to neurofibromatosis is underrecognized and may masquerade Takayasu's arteritis in Asian children. |
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Candida krusei infection presenting as a right ventricular mass in a two month old Infant |
p. 170 |
Suresh V Patted, Prabhu C Halkati, Suresh T Yavagal, Ravikant Patil DOI:10.4103/0974-2069.58324 PMID:20808635The prevalence of fungal infections in newborns and small infants is on the rise consequent to the improved care and survival of preterm babies. Most of these premature infants are immunocompromised and subjected to invasive monitoring and therapy in neonatal intensive care units making them susceptible to nosocomial infections. We report a rare case of right ventricular mass secondary to candida krusei infection which was excised surgically. This article reemphasizes the importance of stringent aseptic practices in neonatal intensive care units to prevent nosocomial infections and the early use of echocardiography in neonates presenting with atypical unexplained symptoms to hasten diagnosis and facilitate timely intervention. |
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Use of Bosentan in neonatal post cardiac surgery pulmonary hypertension |
p. 173 |
Ravindra Pawar, Pankaj Kasar, Swati Garekar, Snehal Kulkarni DOI:10.4103/0974-2069.58325 PMID:20808636We report the use of Bosentan in the post-operative period of a neonate with obstructed infradiaphragmatic total anomalous pulmonary venous connection and severe pulmonary arterial hypertension. To our knowledge, this is the first report of use of Bosentan in this situation. |
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Flash pulmonary edema in a post arterial switch operation - High flow oxygen as a treatment modality |
p. 175 |
Jamuna Kumar, Rajesh Hegde, Sunita Maheshwari, Shekar Rao DOI:10.4103/0974-2069.58326 PMID:20808637We report a case of a 3-year-old boy who underwent an arterial switch operation with relief of left ventricular outflow tract obstruction and later presented with recurrent episodes of flash pulmonary edema. High-flow humidified oxygen with positive pressure support (Vapotherm) was used as a treatment modality, thereby avoiding intubation and mechanical ventilation. |
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IMAGES |
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Pulmonary arteriovenous malformations after cavopulmonary anastomosis |
p. 177 |
Anil Kumar Singhi, R Krishna Kumar PMID:20808638Pulmonary arteriovenous malformation (PAVM) is common after cavopulmonary anastomosis. PAVMs appear on chest X-ray film as diffuse opacity in one or both lungs. Angiographically, it appears as spidery diffuse vascularity with near simultaneous opacification of pulmonary arteries and veins. |
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SELECTED SUMMARIES |
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Selected Summaries |
p. 179 |
Sachin Talwar, Shiv Kumar Choudhary, Balram Airan |
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