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Figure 2: Echocardiography showing a decrease in the pulmonary artery systolic pressure from 104.8 mmHg before the initiation of selexipag (a) to 78 mmHg after 3 months (b). Pulmonary artery systolic pressure was calculated using the following formula: PAP = tricuspid regurgitation gradient (RT) + RA pressure (RAP) = 10 mmHg. PAP: Pulmonary artery systolic pressure; TR: Tricuspid regurgitation gradient; RAP: Right atrial pressure (c) 3D echocardiography showing the crescent-shaped LV (“D-shaped” LV) before selexipag initiation. 3D: Three dimensional; RV: Right ventricle; LV: Left ventricle

Figure 2: Echocardiography showing a decrease in the pulmonary artery systolic pressure from 104.8 mmHg before the initiation of selexipag (a) to 78 mmHg after 3 months (b). Pulmonary artery systolic pressure was calculated using the following formula: PAP = tricuspid regurgitation gradient (RT) + RA pressure (RAP) = 10 mmHg. PAP: Pulmonary artery systolic pressure; TR: Tricuspid regurgitation gradient; RAP: Right atrial pressure (c) 3D echocardiography showing the crescent-shaped LV (“D-shaped” LV) before selexipag initiation. 3D: Three dimensional; RV: Right ventricle; LV: Left ventricle