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Figure 3: These electrocardiograms show 12-lead electrocardiograms taken 10 min apart. Although both show sinus rhythm with 1:1 atrioventricular conduction, the QRS complex is wider at faster heart rates (a) and narrow at slower heart rate (b). The QRS morphology may be called as intraventricular conduction defect as it does not fit into the typical triphasic right bundle branch block pattern. This may be a demonstration of the “use-dependent kinetics” of flecainide, where the Na + channel blockade is more at faster heart rates

Figure 3: These electrocardiograms show 12-lead electrocardiograms taken 10 min apart. Although both show sinus rhythm with 1:1 atrioventricular conduction, the QRS complex is wider at faster heart rates (a) and narrow at slower heart rate (b). The QRS morphology may be called as intraventricular conduction defect as it does not fit into the typical triphasic right bundle branch block pattern. This may be a demonstration of the “use-dependent kinetics” of flecainide, where the Na + channel blockade is more at faster heart rates