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Figure 1: Systems activated in heart failure and pathways blocked by angiotensin-converting enzyme inhibitors, angiotensin receptor blocker, and neprilysin inhibitors. (sympathetic nervous system activation pathway is not shown in the figure). ANP: Atrial natriuretic peptide, BNP: B-type natriuretic peptide, NPS: Natriuretic peptide system, RAAS: Renin angiotensin aldosterone system

Figure 1: Systems activated in heart failure and pathways blocked by angiotensin-converting enzyme inhibitors, angiotensin receptor blocker, and neprilysin inhibitors. (sympathetic nervous system activation pathway is not shown in the figure). ANP: Atrial natriuretic peptide, BNP: B-type natriuretic peptide, NPS: Natriuretic peptide system, RAAS: Renin angiotensin aldosterone system