Ann Pediatr Card Close
 

Figure 3: Pathology. (a) corresponds to the macroscopic examination. The explanted heart weighed 64 g, and contained a large (4 cm × 3.1 cm × 4.3 cm), nonencapsulated, solid, fasciculated, firm, and white/gray mass, without necrosis or cystic degeneration. The mass was localized within the interventricular septum and extended from the apex to the base, including the cardiac crux and comprising the coronary arteries. The tumor was bulging into both ventricles, occupying practically totally both ventricular cavities. The (b)-left image corresponds to the microscopic examination of the tumor obtained by endomyocardial biopsy. The tumor was composed of monomorphic spindle cells arranged in a collagen stroma, with abundant elastic fibers, showing little or no atypia. The anatomopathological study showed infiltrate into the uninvolved cardiac muscle (M) as bands of fibroblasts (F) (H and E, ×100). The (b)-right image corresponds to the microscopic examination of the tumor in the explanted heart. The anatomopathological study revealed a cardiac muscle showing high immunoreactivity for desmin (m) which contracts with fibroblastic cells negativity (f) (Desmin, ×40). T: Tumor, LV: Left ventricle, RV: Right ventricle

Figure 3: Pathology. (a) corresponds to the macroscopic examination. The explanted heart weighed 64 g, and contained a large (4 cm × 3.1 cm × 4.3 cm), nonencapsulated, solid, fasciculated, firm, and white/gray mass, without necrosis or cystic degeneration. The mass was localized within the interventricular septum and extended from the apex to the base, including the cardiac crux and comprising the coronary arteries. The tumor was bulging into both ventricles, occupying practically totally both ventricular cavities. The (b)-left image corresponds to the microscopic examination of the tumor obtained by endomyocardial biopsy. The tumor was composed of monomorphic spindle cells arranged in a collagen stroma, with abundant elastic fibers, showing little or no atypia. The anatomopathological study showed infiltrate into the uninvolved cardiac muscle (M) as bands of fibroblasts (F) (H and E, ×100). The (b)-right image corresponds to the microscopic examination of the tumor in the explanted heart. The anatomopathological study revealed a cardiac muscle showing high immunoreactivity for desmin (m) which contracts with fibroblastic cells negativity (f) (Desmin, ×40). T: Tumor, LV: Left ventricle, RV: Right ventricle